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Gcn5p-dependent acetylation induces degradation of the meiotic transcriptional repressor Ume6p
Ume6p represses early meiotic gene transcription in Saccharomyces cerevisiae by recruiting the Rpd3p histone deacetylase and chromatin-remodeling proteins. Ume6p repression is relieved in a two-step destruction process mediated by the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Th...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Cell Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338428/ https://ncbi.nlm.nih.gov/pubmed/22438583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-06-0536 |
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