A Chemocentric Approach to the Identification of Cancer Targets

A novel chemocentric approach to identifying cancer-relevant targets is introduced. Starting with a large chemical collection, the strategy uses the list of small molecule hits arising from a differential cytotoxicity screening on tumor HCT116 and normal MRC-5 cell lines to identify proteins associa...

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Autors principals: Flachner, Beáta, Lörincz, Zsolt, Carotti, Angelo, Nicolotti, Orazio, Kuchipudi, Praveena, Remez, Nikita, Sanz, Ferran, Tóvári, József, Szabó, Miklós J., Bertók, Béla, Cseh, Sándor, Mestres, Jordi, Dormán, György
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338416/
https://ncbi.nlm.nih.gov/pubmed/22558171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035582
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