Derivation of Human Differential Photoreceptor-like Cells from the Iris by Defined Combinations of CRX, RX and NEUROD

Examples of direct differentiation by defined transcription factors have been provided for beta-cells, cardiomyocytes and neurons. In the human visual system, there are four kinds of photoreceptors in the retina. Neural retina and iris-pigmented epithelium (IPE) share a common developmental origin,...

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Detalhes bibliográficos
Main Authors: Seko, Yuko, Azuma, Noriyuki, Kaneda, Makoto, Nakatani, Kei, Miyagawa, Yoshitaka, Noshiro, Yuuki, Kurokawa, Reiko, Okano, Hideyuki, Umezawa, Akihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338414/
https://ncbi.nlm.nih.gov/pubmed/22558175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035611
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