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Prognostic significance of anti-p53 and anti-KRas circulating antibodies in esophageal cancer patients treated with chemoradiotherapy

BACKGROUND: P53 mutations are an adverse prognostic factor in esophageal cancer. P53 and KRas mutations are involved in chemo-radioresistance. Circulating anti-p53 or anti-KRas antibodies are associated with gene mutations. We studied whether anti-p53 or anti-KRas auto-antibodies were prognostic fac...

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Detalhes bibliográficos
Main Authors: Blanchard, Pierre, Quero, Laurent, Pacault, Vincent, Schlageter, Marie-Helene, Baruch-Hennequin, Valerie, Hennequin, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338390/
https://ncbi.nlm.nih.gov/pubmed/22448886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-119
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