Calpain 3 is important for muscle regeneration: Evidence from patients with limb girdle muscular dystrophies

BACKGROUND: Limb girdle muscular dystrophy (LGMD) type 2A is caused by mutations in the CAPN3 gene and complete lack of functional calpain 3 leads to the most severe muscle wasting. Calpain 3 is suggested to be involved in maturation of contractile elements after muscle degeneration. The aim of this...

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Hlavní autoři: Hauerslev, Simon, Sveen, Marie-Louise, Duno, Morten, Angelini, Corrado, Vissing, John, Krag, Thomas O
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338386/
https://ncbi.nlm.nih.gov/pubmed/22443334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-13-43
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