AAV-mediated human PEDF inhibits tumor growth and metastasis in murine colorectal peritoneal carcinomatosis model

BACKGROUND: Angiogenesis plays an important role in tumor growth and metastasis, therefore antiangiogenic therapy was widely investigated as a promising approach for cancer therapy. Recently, pigment epithelium-derived factor (PEDF) has been shown to be the most potent inhibitor of angiogenesis. Ade...

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Bibliografiske detaljer
Main Authors: Wu, Qin Jie, Gong, Chang Yang, Luo, Shun Tao, Zhang, Dong Mei, Zhang, Shuang, Shi, Hua Shan, Lu, Lian, Yan, Heng Xiu, He, Sha Sha, Li, Dan Dan, Yang, Li, Zhao, Xia, Wei, Yu Quan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338360/
https://ncbi.nlm.nih.gov/pubmed/22462776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-129
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