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Glucocerebrosidase Involvement in Parkinson Disease and Other Synucleinopathies
Mutations in both copies (homozygous or compound heterozygous) of the gene encoding the lysosomal enzyme glucocerebrosidase, which cleaves the glycolipid glucocerebroside into glucose and ceramide cause Gaucher disease. However, multiple independent studies have also reported an association between...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338066/ https://ncbi.nlm.nih.gov/pubmed/22557990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2012.00065 |
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