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DSulfatase-1 fine-tunes Hedgehog patterning activity through a novel regulatory feedback loop
Sulfs are secreted sulfatases that catalyse removal of sulfate from Heparan Sulfate Proteoglycans (HSPGs) in the extracellular space. These enzymes are well known to regulate a number of crucial signalling pathways during development. In this study, we report that DSulfatase-1 (DSulf1), the unique D...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337982/ https://ncbi.nlm.nih.gov/pubmed/21806980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.07.027 |
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