VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission

Synaptic vesicles in the brain harbor several SNARE proteins. With the exception of synaptobrevin2/VAMP2 (syb2) that is directly involved in vesicle fusion, the role of these SNAREs in neurotransmission is unclear. Here, we show that in mice while syb2 drives rapid Ca(2+)-dependent synchronous neuro...

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Detalhes bibliográficos
Main Authors: Raingo, Jesica, Khvotchev, Mikhail, Liu, Pei, Darios, Frederic, Li, Ying C., Ramirez, Denise M.O., Adachi, Megumi, Lemieux, Philippe, Toth, Katalin, Davletov, Bazbek, Kavalali, Ege T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337975/
https://ncbi.nlm.nih.gov/pubmed/22406549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3067
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