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Validation of a Microscale Extraction and High Throughput UHPLC-QTOF-MS Analysis Method for Huperzine A in Huperzia: Microscale UHPLC-MS Analysis of Huperzine A

Herein we report on an improved method for the microscale extraction of huperzine A (HupA), an acetylcholinesterase-inhibiting alkaloid, from as little as 3 mg of tissue homogenate from the clubmoss Huperzia squarrosa (G. Forst.) Trevis with 99.95 % recovery. We also validated a novel UHPLC-QTOF-MS...

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Библиографические подробности
Главные авторы: Cuthbertson, Daniel, Piljac-Žegarac, Jasenka, Lange, Bernd Markus
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337887/
https://ncbi.nlm.nih.gov/pubmed/22275140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.2677
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