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Processing of proteins in autophagy vesicles of antigen-presenting cells generates citrullinated peptides recognized by the immune system

Our laboratory has been investigating for some time the nature of the response of T lymphocytes in autoimmunity in the reactions against self-proteins that result in a number of diseases, such as type 1 diabetes, multiple sclerosis, rheumatoid arthritis (RA) and others. T cells recognize peptides ge...

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Autori principali: Ireland, Jamie M., Unanue, Emil R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337845/
https://ncbi.nlm.nih.gov/pubmed/22361580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19261
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