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Diminished performance on neuropsychological testing in late life depression is correlated with microstructural white matter abnormalities

BACKGROUND: Traditional T2 weighted MR imaging results are non-specific for the extent of underlying white matter structural abnormalities present in late life depression (LLD). Diffusion tensor imaging provides a unique opportunity to investigate the extent and nature of structural injury, but has...

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Autors principals: Mettenburg, Joseph M, Benzinger, Tammie L.S., Shimony, Joshua S, Snyder, Abraham Z., Sheline, Yvette I
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337766/
https://ncbi.nlm.nih.gov/pubmed/22487548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2012.02.044
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