Differential Innate Immune Responses to Low or High Dose Oral SIV Challenge in Rhesus Macaques

Mucosal transmission of HIV predominately occurs during sexual intercourse or breast-feeding and generally results in a successful infection from just one or few founder virions. Here we assessed the impact of viral inoculum size on both viral and immune events within two groups of Rhesus macaques t...

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Main Authors: Durudas, Andre, Chen, Hui-Ling, Gasper, Melanie A., Sundaravaradan, Vasudha, Milush, Jeffrey M., Silvestri, Guido, Johnson, Welkin, Giavedoni, Luis D., Sodora, Donald L.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337698/
https://ncbi.nlm.nih.gov/pubmed/21861823
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