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In vivo Polycomb kinetics and mitotic chromatin binding distinguish stem cells from differentiated cells
Epigenetic memory mediated by Polycomb group (PcG) proteins must be maintained during cell division, but must also be flexible to allow cell fate transitions. Here we quantify dynamic chromatin-binding properties of PH::GFP and PC::GFP in living Drosophila in two cell types that undergo defined diff...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337459/ https://ncbi.nlm.nih.gov/pubmed/22508729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.184648.111 |
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