Endosomal sorting by Semaphorin 4A in retinal pigment epithelium supports photoreceptor survival

Photoreceptor cell death is the hallmark of a group of human inherited retinal degeneration. Although the causative genetic mutations are often known, the mechanisms leading to photoreceptor degeneration remain poorly defined. Here, we show that Semaphorin 4A (Sema4A), a member of axonal guidance mo...

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Autores principales: Toyofuku, Toshihiko, Nojima, Satoshi, Ishikawa, Takako, Takamatsu, Hyota, Tsujimura, Tohru, Uemura, Akiyoshi, Matsuda, Junko, Seki, Takaharu, Kumanogoh, Atsushi
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337456/
https://ncbi.nlm.nih.gov/pubmed/22465952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.184481.111
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