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The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children

BACKGROUND: Patients showed a different response following intravenous midazolam injection. Some children showed irritability or were not sedated by midazolam. We hypothesized that there may be genetic variations of the MDR1 gene, based on the response to midazolam. METHODS: One hundred and ninety-t...

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Autors principals: Byon, Hyo-Jin, Park, Keun-Suk, Park, Yong-Hee, Kim, Jin-Tae, Jung, Chul-Woo, Kim, Hee-Soo
Format: Artigo
Idioma:Inglês
Publicat: The Korean Society of Anesthesiologists 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337379/
https://ncbi.nlm.nih.gov/pubmed/22558499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4097/kjae.2012.62.4.332
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