Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish

We identified three zebrafish mutants with defects in biliary development. One of these mutants, pekin (pn), also demonstrated generalized hypopigmentation and other defects, including disruption of retinal cell layers, lack of zymogen granules in the pancreas, and dilated Golgi in intestinal epithe...

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Autors principals: EauClaire, Steven F., Cui, Shuang, Ma, Liyuan, Matous, James, Marlow, Florence L., Gupta, Tripti, Burgess, Harold A., Abrams, Elliott W., Kapp, Lee D., Granato, Michael, Mullins, Mary C., Matthews, Randolph P.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337356/
https://ncbi.nlm.nih.gov/pubmed/22465374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.03.009
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