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Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system

Glioblastoma multiforme (GBM) is the most frequent malignant brain tumor in adults. Its established first-line adjuvant treatment is radiotherapy in combination with temozolomide (TZM). Hematotoxicity is listed as a frequent adverse drug reaction in the US prescribing information and hepatotoxicity...

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Detalhes bibliográficos
Main Authors: Sarganas, Giselle, Orzechowski, Hans D., Klimpel, Andreas, Thomae, Michael, Kauffmann, Wolfgang, Herbst, Hermann, Bronder, Elisabeth, Garbe, Edeltraut
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337307/
https://ncbi.nlm.nih.gov/pubmed/22394496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos056
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