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The 5' end domain of U2 snRNA is required to establish the interaction of U2 snRNP with U2 auxiliary factor(s) during mammalian spliceosome assembly.

Stable association of U2 snRNP with the branchpoint sequence of mammalian pre-mRNAs requires binding of a non-snRNP protein to the polypyrimidine tract. In order to determine how U2 snRNP contacts this protein, we have used an RNA containing the consensus 5' and the (Py)n-AG 3' splice sites but lack...

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Udgivet i:Nucleic Acids Res
Principais autores: Khellil, S, Daugeron, M C, Alibert, C, Jeanteur, P, Cathala, G, Brunel, C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1991
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333725/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1850127/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.4.877
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