Retroviral integrase domains: DNA binding and the recognition of LTR sequences.
Integration of retroviral DNA into the host chromosome requires a virus-encoded integrase (IN). IN recognizes, cuts and then joins specific viral DNA sequences (LTR ends) to essentially random sites in host DNA. We have used computer-assisted protein alignments and mutagenesis in an attempt to local...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1991
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1850126/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.4.851 |
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