Expression of Escherichia coli virulence usher protein attenuates wild-type Salmonella

Generation of a live attenuated vaccine for bacterial pathogens often requires prior knowledge of the pathogen’s virulence factors. We hypothesized an alternative approach of heterologous gene expression would make a wild-type (wt) pathogen more susceptible to host cell killing, thus, resulting in i...

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Detalhes bibliográficos
Main Authors: Yang, Xinghong, Suo, Zhiyong, Thornburg, Theresa, Holderness, Kathryn, Cao, Ling, Lim, Timothy, Walters, Nancy, Kellerman, Laura, Loetterle, Linda, Avci, Recep, Pascual, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337150/
https://ncbi.nlm.nih.gov/pubmed/22286706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/viru.3.1.18447
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