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Facile synthesis of 4-vinyl- and 4-fluorovinyl-1,2,3-triazoles via bifunctional “click-olefination” reagents

Modular synthesis of vinyl and fluorovinyl triazoles can be achieved from bifunctional propargyl and fluoropropargyl sulfones by Cu-catalyzed azide-alkyne ligation and Julia-Kocienski olefination. Competitive click reactions of the protio and fluoropropargyl sulfones show higher reactivity of the la...

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Detalhes bibliográficos
Main Authors: Kumar, Rakesh, Pradhan, Padmanava, Zajc, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337081/
https://ncbi.nlm.nih.gov/pubmed/21336351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc05083k
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