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Interaction of HIV-1 reverse transcriptase with a synthetic form of its replication primer, tRNA(Lys,3).
Using synthetic oligonucleotides, a gene encoding the HIV-1 replication primer, tRNA(Lys,3), was constructed and placed downstream from a bacteriophage T7 promoter. In vitro transcription of this gene yielded a form of tRNA(Lys,3) which lacks the modified bases characteristic of the natural species...
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| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1991
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC333707/ https://ncbi.nlm.nih.gov/pubmed/1708122 |
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