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Interleukin-1beta Causes Fluoxetine Resistance in an Animal Model of Epilepsy-Associated Depression

Depression represents a common comorbidity of epilepsy and is frequently resistant to selective serotonin reuptake inhibitors (SSRI). We tested the hypothesis that the SSRI resistance in epilepsy associated depression may be a result of a pathologically enhanced interleukin-1β (IL1-β) signaling, and...

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Autors principals: Pineda, Eduardo A., Hensler, Julie G., Sankar, Raman, Shin, Don, Burke, Teresa F., Mazarati, Andréy M.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337012/
https://ncbi.nlm.nih.gov/pubmed/22427156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-012-0110-4
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