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Treating myeloma cast nephropathy without treating myeloma
Cast nephropathy is the result of coprecipitation of immunoglobulin free light chains (FLCs) with Tamm-Horsfall glycoprotein (THP). It is a hallmark of multiple myeloma that has significant consequences. Treatment strategies in the past focused on reduction of serum FLC by control of the myeloma. In...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337000/ https://ncbi.nlm.nih.gov/pubmed/22484811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63248 |
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