Agreement in Risk Prediction Between the 21-Gene Recurrence Score Assay (Oncotype DX®) and the PAM50 Breast Cancer Intrinsic Classifier™ in Early-Stage Estrogen Receptor–Positive Breast Cancer

PURPOSE. To compare risk assignment by PAM50 Breast Cancer Intrinsic Classifier™ and Oncotype DX_Recurrence Score (RS) in the same population. METHODS. RNA was extracted from 151 estrogen receptor (ER)(+) stage I–II breast cancers and gene expression profiled using PAM50 “intrinsic” subtyping test....

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Main Authors: Kelly, Catherine M., Bernard, Philip S., Krishnamurthy, Savitri, Wang, Bailiang, Ebbert, Mark T.W., Bastien, Roy R.L., Boucher, Kenneth M., Young, Elliana, Iwamoto, Takayuki, Pusztai, Lajos
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2012
Assuntos:
Breast Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336833/
https://ncbi.nlm.nih.gov/pubmed/22418568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2012-0007
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