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Stereoselective Interaction of Pantoprazole with ABCG2. II. In Vitro Flux Analysis
(−)Pantoprazole [(−)PAN] accumulated in rat milk stereoselectively, and this accumulation was attributed to rat Abcg2 (rAbcg2). In contrast, flux experiments at 25 μM showed that (+)pantoprazole [(+)PAN] was preferentially transported by rAbcg2. The purpose of the current study was to comprehensivel...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336798/ https://ncbi.nlm.nih.gov/pubmed/22355035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.041616 |
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