Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway

Body weight is regulated by coordinating energy intake and energy expenditure. Transforming growth factor β (TGFβ)/bone morphogenetic protein (BMP) signaling has been shown to regulate energy balance in lower organisms, but whether a similar pathway exists in mammals is unknown. We have previously d...

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Détails bibliographiques
Auteurs principaux: Townsend, Kristy L., Suzuki, Ryo, Huang, Tian Lian, Jing, Enxuan, Schulz, Tim J., Lee, Kevin, Taniguchi, Cullen M., Espinoza, Daniel O., McDougall, Lindsay E., Zhang, Hongbin, He, Tong-Chuan, Kokkotou, Efi, Tseng, Yu-Hua
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2012
Sujets:
Research Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336788/
https://ncbi.nlm.nih.gov/pubmed/22331196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-199067
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