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Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude

Pregnancy at high altitude is associated with a reduction in birth weight of ∼100 g/1000 m of ascent. The underlying mechanisms are unclear but may involve alteration in energy-demanding activities, such as protein synthesis. To test this hypothesis, both in vivo and in vitro approaches were used. P...

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Bibliografiska uppgifter
Huvudupphovsmän: Yung, Hong Wa, Cox, Mathew, Tissot van Patot, Martha, Burton, Graham J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Federation of American Societies for Experimental Biology 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336782/
https://ncbi.nlm.nih.gov/pubmed/22267338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-190082
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