ERK1 is important for Th2 differentiation and development of experimental asthma

The ERK1/2 signaling pathway regulates a variety of T-cell functions. We observed dynamic changes in the expression of ERK1/2 during T-helper cell differentiation. Specifically, the expression of ERK1/2 was decreased and increased by IL-12 and IL-4, respectively. To address this subject further, we...

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Bibliografski detalji
Glavni autori: Goplen, Nicholas, Karim, Zunayet, Guo, Lei, Zhuang, Yonghua, Huang, Hua, Gorska, Magdalena M., Gelfand, Erwin, Pagés, Gilles, Pouysségur, Jacques, Alam, Rafeul
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2012
Teme:
Research Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336776/
https://ncbi.nlm.nih.gov/pubmed/22262639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-196477
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