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Krüppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleen

The development and survival of NK cells rely on a complex, spatiotemporal gene expression pattern regulated by specific transcription factors in NK cells and tissue-specific microenvironments supported by hematopoietic cells. Here, we show that somatic deletion of the KLF4 gene, using inducible and...

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Detalhes bibliográficos
Main Authors: Shik Park, Chun, Lee, Ping-Hsien, Yamada, Takeshi, Burns, Audrea, Shen, Ye, Puppi, Monica, Lacorazza, H. Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336774/
https://ncbi.nlm.nih.gov/pubmed/22345706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0811413
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