Expansion of a subset of CD14(high)CD16(neg)CCR2(low/neg) monocytes functionally similar to myeloid-derived suppressor cells during SIV and HIV infection

Monocytes have been categorized in three main subpopulations based on CD14 and CD16 surface expression. Classical monocytes express the CD14(++)CD16(−)CCR2(+) phenotype and migrate to inflammatory sites by quickly responding to CCL2 signaling. Here, we identified and characterized the expansion of a...

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Main Authors: Gama, Lucio, Shirk, Erin N., Russell, Julia N., Carvalho, Karina I., Li, Ming, Queen, Suzanne E., Kalil, Jorge, Christine Zink, M., Clements, Janice E., Kallas, Esper G.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2012
Fag:
Host Defense & Pathophysiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336772/
https://ncbi.nlm.nih.gov/pubmed/22368280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1111579
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