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Contributions of IBD5, IL23R, ATG16L1, and NOD2 to Crohn’s Disease Risk in a Population-Based Case-Control Study: Evidence of Gene–Gene Interactions

BACKGROUND: IBD5, IL23R, and ATG16L1 genetic variations are established Crohn’s disease (CD) risks alleles. We evaluated these in a population-based case-control study within a cohort to determine their penetrance, population attributable risk, independence, and relationship to other established CD...

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Detalhes bibliográficos
Main Authors: Okazaki, Toshihiko, Wang, Ming-Hsi, Rawsthorne, Patricia, Sargent, Michael, Datta, Lisa Wu, Shugart, Yin Yao, Bernstein, Charles N., Brant, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336049/
https://ncbi.nlm.nih.gov/pubmed/18521914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.20512
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