The yeast DNA ligase gene CDC9 is controlled by six orientation specific upstream activating sequences that respond to cellular proliferation but which alone cannot mediate cell cycle regulation.

By fusing the CDC9 structural gene to the PGK upstream sequences and the CDC9 upstream to lacZ, we showed that the cell cycle expression of CDC9 is largely due to transcriptional regulation. To investigate the role of six ATGATT upstream repeats in CDC9 regulation, synthetic copies of the sequence w...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: White, J H, Johnson, A L, Lowndes, N F, Johnston, L H
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1991
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333602/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1901644/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.2.359
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