Is there a higher genetic load of susceptibility loci in familial ankylosing spondylitis?

OBJECTIVE: Several genetic risk variants for ankylosing spondylitis (AS) have been identified in genome wide association studies. Our objective was to examine whether familial AS cases have a higher genetic load of these susceptibility variants. METHODS: Overall, 502 AS patients were examined, consi...

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Detalhes bibliográficos
Main Authors: Joshi, Reeti, Reveille, John D., Brown, Matthew A., Weisman, Michael H., Ward, Michael M., Gensler, Lianne S., Wordsworth, B. Paul, Evans, David M., Assassi, Shervin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335985/
https://ncbi.nlm.nih.gov/pubmed/22231927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acr.21601
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