Germline BAP1 Inactivation Is Preferentially Associated with Metastatic Ocular Melanoma and Cutaneous-Ocular Melanoma Families

BACKGROUND: BAP1 has been shown to be a target of both somatic alteration in high-risk ocular melanomas (OM) and germline inactivation in a few individuals from cancer-prone families. These findings suggest that constitutional BAP1 changes may predispose individuals to metastatic OM and that familia...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Njauw, Ching-Ni Jenny, Kim, Ivana, Piris, Adriano, Gabree, Michele, Taylor, Michael, Lane, Anne Marie, DeAngelis, Margaret M., Gragoudas, Evangelos, Duncan, Lyn M., Tsao, Hensin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335872/
https://ncbi.nlm.nih.gov/pubmed/22545102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035295
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