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Novel Regulatory Mechanisms for Generation of the Soluble Leptin Receptor: Implications for Leptin Action
BACKGROUND: The adipokine leptin realizes signal transduction via four different membrane-anchored leptin receptor (Ob-R) isoforms in humans. However, the amount of functionally active Ob-R is affected by constitutive shedding of the extracellular domain via a so far unknown mechanism. The product o...
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| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335825/ https://ncbi.nlm.nih.gov/pubmed/22545089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034787 |
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