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The Hepatitis E Virus Polyproline Region Is Involved in Viral Adaptation

Genomes of hepatitis E virus (HEV), rubivirus and cutthroat virus (CTV) contain a region of high proline density and low amino acid (aa) complexity, named the polyproline region (PPR). In HEV genotypes 1, 3 and 4, it is the only region within the non-structural open reading frame (ORF1) with positiv...

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Detalhes bibliográficos
Main Authors: Purdy, Michael A., Lara, James, Khudyakov, Yury E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335810/
https://ncbi.nlm.nih.gov/pubmed/22545153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035974
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