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The NLRP3 inflammasome is active but not essential in endotoxin-induced uveitis

OBJECTIVE: The inflammasome complex involving caspase-1 and nucleotide-binding domain, leucine-rich repeat containing protein (NLRP)3, also known as NALP3 or cryopyrin is important for host responses to microbial pathogens and several autoinflammatory diseases. We investigated the extent to which NL...

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Hlavní autoři: Rosenzweig, Holly L., Woods, April, Clowers, Jenna S., Planck, Stephen R., Rosenbaum, James T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335428/
https://ncbi.nlm.nih.gov/pubmed/22119862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-011-0404-8
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