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Hedgehog signaling in myofibroblasts directly promotes prostate tumor cell growth

Despite strong evidence for the involvement of the stroma in Hedgehog signaling, little is known about the identity of the stromal cells and the signaling mechanisms that mediate the growth promoting effect of Hh signaling. We developed an in vitro co-culture model using microchannel technology to e...

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Detalhes bibliográficos
Main Authors: Domenech, Maribella, Bjerregaard, Robert, Bushman, Wade, Beebe, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335396/
https://ncbi.nlm.nih.gov/pubmed/22234342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1ib00104c
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