Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity

Natural killer (NK) cells are innate lymphocytes that play an important role against viral infections and cancer. This effect is achieved through a complex mosaic of inhibitory and activating receptors expressed by NK cells that ultimately determine the magnitude of the NK-cell response. The T-cell...

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Autors principals: Ndhlovu, Lishomwa C., Lopez-Vergès, Sandra, Barbour, Jason D., Jones, R. Brad, Jha, Aashish R., Long, Brian R., Schoeffler, Eric C., Fujita, Tsuyoshi, Nixon, Douglas F., Lanier, Lewis L.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335380/
https://ncbi.nlm.nih.gov/pubmed/22383801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-392951
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