Inhibition of SV40 gene expression by microinjected small antisense RNA and DNA molecules

We tested the impact of antisense RNA and DNA molecules on SV40 gene expression by microinjection into TC7 cells. Short antisense stretches, complementary to either hairpin or loop structures on the T antigen mRNA, inhibited T antigen synthesis. In contrast, full-length antisense RNA and DNA molecul...

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Bibliografiske detaljer
Main Authors: Graessmann, M., Michaels, G., Berg, B., Graessmann, A.
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC333533/
https://ncbi.nlm.nih.gov/pubmed/1849259
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