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Expression profiling of uterine leiomyomata cytogenetic subgroups reveals distinct signatures in matched myometrium: transcriptional profiling of the t(12;14) and evidence in support of predisposing genetic heterogeneity

Uterine leiomyomata (UL), the most common neoplasm in reproductive-age women, are classified into distinct genetic subgroups based on recurrent chromosome abnormalities. To develop a molecular signature of UL with t(12;14)(q14-q15;q23-q24), we took advantage of the multiple UL arising as independent...

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Detalhes bibliográficos
Main Authors: Hodge, Jennelle C., Kim, Tae-Min, Dreyfuss, Jonathan M., Somasundaram, Priya, Christacos, Nicole C., Rousselle, Marissa, Quade, Bradley J., Park, Peter J., Stewart, Elizabeth A., Morton, Cynthia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335314/
https://ncbi.nlm.nih.gov/pubmed/22343407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds051
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