Ets-1 Is Essential for Connective Tissue Growth Factor (CTGF/CCN2) Induction by TGF-β1 in Osteoblasts

BACKGROUND: Ets-1 controls osteoblast differentiation and bone development; however, its downstream mechanism of action in osteoblasts remains largely undetermined. CCN2 acts as an anabolic growth factor to regulate osteoblast differentiation and function. CCN2 is induced by TGF-β1 and acts as a med...

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Autors principals: Geisinger, Max T., Astaiza, Randy, Butler, Tiffany, Popoff, Steven N., Planey, Sonia Lobo, Arnott, John A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335151/
https://ncbi.nlm.nih.gov/pubmed/22539964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035258
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