Retinal Gene Expression Changes Related to IOP Exposure and Axonal Loss in DBA/2J Mice

PURPOSE. To determine the effects of cumulative IOP exposure and axonal damage on retinal gene expression in DBA/2 mice. METHODS. DBA/2J, DBA/2J(pe) (pearl), and C57BL/6 mice from 3 to 12 months of age were used. IOP was measured with a rebound tonometer, and optic nerve (ON) damage was determined b...

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Main Authors: Panagis, Lambros, Zhao, Xiujun, Ge, Yongchao, Ren, Lizhen, Mittag, Thomas W., Danias, John
Format: Artigo
Sprog:Inglês
Udgivet: Association for Research in Vision and Ophthalmology, Inc. 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335131/
https://ncbi.nlm.nih.gov/pubmed/21908583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-7063
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