Cyr61/CCN1 Is Regulated by Wnt/β-Catenin Signaling and Plays an Important Role in the Progression of Hepatocellular Carcinoma

Abnormal activation of the canonical Wnt signaling pathway has been implicated in carcinogenesis. Transcription of Wnt target genes is regulated by nuclear β-catenin, whose over-expression is observed in Hepatocellular Carcinoma (HCC) tissue. Cyr61, a member of the CCN complex family of multifunctio...

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Autores principales: Li, Zhi-Qiang, Ding, Wei, Sun, Shi-Jun, Li, Jun, Pan, Jing, Zhao, Chen, Wu, Wei-Ru, Si, Wei-Ke
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335098/
https://ncbi.nlm.nih.gov/pubmed/22540002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035754
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