Cyr61/CCN1 Is Regulated by Wnt/β-Catenin Signaling and Plays an Important Role in the Progression of Hepatocellular Carcinoma

Abnormal activation of the canonical Wnt signaling pathway has been implicated in carcinogenesis. Transcription of Wnt target genes is regulated by nuclear β-catenin, whose over-expression is observed in Hepatocellular Carcinoma (HCC) tissue. Cyr61, a member of the CCN complex family of multifunctio...

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Main Authors: Li, Zhi-Qiang, Ding, Wei, Sun, Shi-Jun, Li, Jun, Pan, Jing, Zhao, Chen, Wu, Wei-Ru, Si, Wei-Ke
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335098/
https://ncbi.nlm.nih.gov/pubmed/22540002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035754
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