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Evaluation of Leishmania donovani Protein Disulfide Isomerase as a Potential Immunogenic Protein/Vaccine Candidate against Visceral Leishmaniasis

In Leishmania species, Protein disulfide isomerase (PDI) - a redox chaperone, is reported to be involved in its virulence and survival. This protein has also been identified, through proteomics, as a Th1 stimulatory protein in the soluble lysate of a clinical isolate of Leishmania donovani (LdPDI)....

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Detalhes bibliográficos
Main Authors: Kushawaha, Pramod Kumar, Gupta, Reema, Tripathi, Chandra Dev Pati, Sundar, Shyam, Dube, Anuradha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335089/
https://ncbi.nlm.nih.gov/pubmed/22539989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035670
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