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Antibody Recognition of Cancer-Related Gangliosides and Their Mimics Investigated Using in silico Site Mapping

Modified gangliosides may be overexpressed in certain types of cancer, thus, they are considered a valuable target in cancer immunotherapy. Structural knowledge of their interaction with antibodies is currently limited, due to the large size and high flexibility of these ligands. In this study, we a...

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Detalles Bibliográficos
Main Authors: Agostino, Mark, Yuriev, Elizabeth, Ramsland, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334985/
https://ncbi.nlm.nih.gov/pubmed/22536387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035457
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