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The Effects of NMDA Subunit Composition on Calcium Influx and Spike Timing-Dependent Plasticity in Striatal Medium Spiny Neurons

Calcium through NMDA receptors (NMDARs) is necessary for the long-term potentiation (LTP) of synaptic strength; however, NMDARs differ in several properties that can influence the amount of calcium influx into the spine. These properties, such as sensitivity to magnesium block and conductance decay...

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Autori principali: Evans, Rebekah C., Morera-Herreras, Teresa, Cui, Yihui, Du, Kai, Sheehan, Tom, Kotaleski, Jeanette Hellgren, Venance, Laurent, Blackwell, Kim T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334887/
https://ncbi.nlm.nih.gov/pubmed/22536151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002493
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