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C. elegans detects pathogen-induced translational inhibition to activate immune signaling

Pathogens commonly disrupt host cell processes or cause damage, but the surveillance mechanisms used by animals to monitor these attacks are poorly understood. Upon infection with pathogenic Pseudomonas aeruginosa, the nematode C. elegans upregulates infection response gene irg-1 using the zip-2 bZI...

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Detalhes bibliográficos
Main Authors: Dunbar, Tiffany L., Yan, Zhi, Balla, Keir M., Smelkinson, Margery G., Troemel, Emily R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334869/
https://ncbi.nlm.nih.gov/pubmed/22520465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.02.008
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